Downloads of the M-ZDOCK program are available for Linux, IBM p690, and Mac OS X platforms.
M-ZDOCK is based on the concept that a Cn multimer can be generated by putting two adjacent subunits anywhere in the plane that is perpendicular to the axis of rotation (the subunits just need to be rotated 360/n degrees from each other in this plane). We wrote an applet to show this concept, where you can vary the degree of symmetry, the shape of the subunits, and show/hide the rest of the multimer. If you have trouble loading the applet, you may need JRE 1.4.2.
Table listing the residues for each multimer testcase that moved significantly upon binding, consequently ignored for evaluation of the rigid-body predictions.
Reference: Pierce B, Weng Z (2005) "M-ZDOCK: A Grid-based Approach for Cn Symmetric Multimer Docking." Bioinformatics 21(8), 1472-1476.
Please send suggestions to: Brian Pierce